Efficient Reduction of Acyl Chlorides with Zn(BH4)2/N,N,N′,N′-Tetramethylethylenediamine
نویسندگان
چکیده
منابع مشابه
Observation of 1,3-diketones formation in the reaction of bulky acyl chlorides with methyllithium.
The formation of 1,3-diketones was observed in the reactions of bulky acyl chlorides with methyllithium. The reaction products depend on the steric hindrance around the carbonyl group of the acyl chloride and the electronic effect of the group(s) linked to the carbonyl. When the steric hindrance around the carbonyl group of the acyl chloride is big enough, the 1,3-diketone is the only product. ...
متن کاملVisible Light Photoredox Cross-Coupling of Acyl Chlorides with Potassium Alkoxymethyltrifluoroborates: Synthesis of α-Alkoxyketones
A visible-light, single-electron-transfer (SET), photoredox cross-coupling for the synthesis of α-alkoxyketones has been developed. In this method, various aliphatic and aromatic acyl chlorides were successfully coupled with structurally diverse potassium alkoxymethyltrifluoroborates, producing the corresponding α-alkoxyketones with high yields. In this operationally simple and mild cross-coupl...
متن کاملRoom temperature palladium catalysed coupling of acyl chlorides with terminal alkynes.
Conditions are reported for the facile, high-yielding coupling of acyl chlorides with terminal alkynes in a reaction involving palladium and copper iodide; the reaction is tolerant of a wide variety of acyl chlorides and terminal alkynes and provides a convenient one-pot route to acetylenic ketones.
متن کاملCopper(II)-catalyzed ortho-functionalization of 2-arylpyridines with acyl chlorides.
Copper-catalyzed ortho-benzoxylation of 2-arylpyridine sp(2) C-H bonds with acyl chloride is described. Notably, switching the base from t-BuOK to Li(2)CO(3) causes chlorination of the C-H bond to take place.
متن کاملDirect β-acylation of 2-arylidene-1,3-indandiones with acyl chlorides catalyzed by organophosphanes.
We have developed an organophosphane-catalyzed direct β-acylation of a series of conjugated systems bearing ketone, amide and ester functionalities using acyl chlorides as trapping reagents. A wide variety of highly functional ketone derivatives were generated efficiently under very mild conditions with high yields according to our protocol. Our adducts can even be utilized as important buildin...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 1988
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.61.2684